Macrolides, tetracyclines, oxazolidinones

In: Nursing

Macrolides, tetracyclines, oxazolidinones (e.g., linezolid), and aminoglycosides all produce their antibacterial effects by inhibiting bacterial protein…

Macrolides, tetracyclines, oxazolidinones (e.g., linezolid), and aminoglycosides all produce their antibacterial effects by inhibiting bacterial protein synthesis; however, each drug class has distinct uses.

  • Why is azithromycin, but not doxycycline, most commonly used for treating community acquired pneumonia?
  • If gentamicin is a bactericidal drug and linezolid is only bacteriostatic, why is linezolid generally considered the more restricted-use antibiotic and more “powerful” for treating Gram-positive infections?

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